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Read nowCellular immunity and PRRS control
- Expertise video
- Dr. Michael Rahe
Following infection via inhalation of aerosolized virus, PRRS virus replicates in pulmonary alveolar macrophages in the lung.
Viremia and shedding of PRRSV AUT15-33 (“acro” PRRSV) by vaccinated and nonvaccinated piglets
- 10 minutes
- Expertise article
- Dürlinger S., Balka G., RathkjenPH., Kraft C., Morgenstern R., Knecht C., Zaruba M., Rümenapf T., Ladinig A.
The aim of the present study was testing of the efficacy of Ingelvac PRRSFLEX EU in decreasing viremia levels and viral shedding in piglets after a challenge with a virulent PRRSV-1- isolate (PRRSV AUT15-33) causing severe clinical problems in the field.
Changes in the Epidemiology of PCV2 are relevant
- 2 minutes
- Bite size
- Quim Segalés
Meet the Expert Bite Sizes with Quim Segalés.
Cell-mediated immune response and protective efficacy of porcine reproductive and respiratory syndrome virus modified-live vaccines against co-challenge with PRRSV-1 and PRRSV-2
- Expertise article
- Madapong et al., 2020
Cell-mediated immunity (CMI), IL-10, and the protective efficacy of modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccines (MLV) against co-challenge with PRRSV-1 and PRRSV-2 (HP-PRRSV) were investigated.
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What are possible ways pig gets infected with ASF in Europe, Asia or America?
- 3 minutes
- Bite size
- Klaus Depner
Meet the Expert Bite Sizes with Klaus Depner.
Vaccination with PRRS type 2 strain against high pathogenic type 1 virus in growing pigs in Korea
- 10 minutes
- Expertise article | IPVS 2016
- JY Choi, TW Hahn, HK Seo. IPVS. 2016
In this study, it is concluded that a Type 2 strain based modified live vaccine could reduce the impact of the highly pathogenic PRRS wild type 1 virus. This is consistent with other researchers’ findings
European PRRSpective 2023 - Value of climbing up the ladder
- 21 minutes
- European PRRSpective | Expertise video
- Daniel Linhares
European PRRSpective 2023 session 2 Controlling farm breakdowns
Correlation of Neutralizing Antibodies (NAbs) between Sows and Piglets and Evaluation of Protectability Associated with Maternally Derived NAbs in Pigs against Circulating Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) under Field Conditions
- Top publications | June
- Fu-Chun Hsueh, Sheng-Yuan Wang, Wei-Hao Lin, Chuen-Fu Lin, Chen-Yu Tsai, Chin-Wen Huang, Ning Sun, Ming-Tang Chiou and Chao-Nan Lin
Porcine reproductive and respiratory syndrome (PRRS), which is caused by a highly transmissible pathogen called porcine reproductive and respiratory syndrome virus (PRRSV), has caused severe problems, including reproductive disorders in sows and respiratory symptoms in nursery pigs worldwide, since the early 1990s. However, currently available PRRSV vaccines do not supply complete immunity to confront the viral infection. Elicitation of PRRSV-specific neutralizing antibodies (NAbs) during the preinfectious period has been deemed to be a feasible strategy to modulate this virus, especially in farms where nursery pigs are seized with PRRSVs. A total of 180 piglets in a farrow-to-finish farm that had a natural outbreak of PRRS were distributed into three groups based on the different PRRSV NAbs levels in their dams. In the present study, piglets that received superior maternal-transferred NAbs showed delayed and relatively slight viral loads in serum and, on the whole, higher survival rates against wild PRRSV infections. A positive correlation of maternal NAbs between sows and their piglets was identified; moreover, high NAbs titers in piglets can last for at least 4 weeks. These results provide updated information to develop an appropriate immune strategy for breeding and for future PRRSV control under field conditions.